Plugging the Antibiotics Gap: A Medicinal Chemist’s Perspective

Join the UK Science Chemistry Innovation (SCI) forum on the antibiotic drug discovery pipeline - 16 November 2016, Cheshire, UK

Plugging the Antibiotics Gap: A Medicinal Chemist’s Perspective
Wednesday 16 November 2016, Alderley Park Conference Centre, Cheshire, UK

Event poster

Register today T: + (0)207 7598 1561 E: 

Sustained under-investment in antimicrobials has led to a severe shortage of new drugs for treating infection. At a time when emerging antimicrobial resistance is decreasing the efficacy of existing treatments, it is more important than ever that we refresh the drug pipeline with new antimicrobials displaying novel modes of action.

Faced with this growing healthcare issue, renewed interest from both industry and academia has led to a resurgence in antimicrobial drug discovery. This meeting will examine the current state of the art from a medicinal chemist’s perspective and will focus on the particular challenges associated with discovering and developing new antimicrobials. Speakers from industry and academia will describe their own strategies for addressing these challenges whilst showcasing the opportunity for creativity and innovation.

Bringing together leading exponents in the field, the meeting will appeal to anyone with an interest in antimicrobial resistance and antimicrobial drug discovery. With great opportunities for academic–industrial partnerships, researchers from both sectors will benefit from the networking opportunities that the meeting will also offer. SCI Members can claim CPD points for attending this conference.

Call for Posters
Anyone wishing to present their research in the Poster Session is encouraged to submit a one-page abstract to by Friday 30 September 2016 with ‘#AntibioticGap2016 - Poster Abstract’ in the subject line. Selected poster presenters will also have the opportunity to give a flash presentation.

Exhibition and Sponsorship
The exhibition, posters and all refreshments will be situated in a single area just outside of the lecture theatre, ensuring excellent access to delegates throughout the meeting. If you are interested in exhibiting at this event or in sponsorship opportunities, please contact for further information and costs.

Register today T: + (0)207 7598 1561 E:

Early-bird rates before 30 September Standard rates after 30 September
SCI/RSC Members £50 SCI/RSC Members £80
SCI/RSC Student Members £30 SCI/RSC Student Members £50
Non-Members £100 Non-Members £160

Join SCI’s Fine Chemicals Group and RSC’s Biological and Medicinal Chemistry Sector during World. Antibiotic Awareness Week 2016 for talks by leading exponents in the field of antimicrobial resistance and antimicrobial drug discovery.

The meeting will take place at the Alderley Park Conference Centre, Cheshire, which is on the Alderley Park research site, a hot spot for antibiotics research, having recently received £4 Million of government funding to establish a new antibiotics research hub.


10.00 Registration and refreshments

10.45 Opening remarks

10.50 The global challenge of antibacterial drug resistance: what can be done?
Prof Laura Piddock, University of Birmingham and Director Antibiotic Action, UK

11.35 A brave new world: Novel Tricyclic Topoisomerase Inhibitors (NTTIs) with potent activity against drug-resistant bacteria
Dr Anthony Huxley, Redx Pharma, Cheshire, UK

12.05 Discovery of small molecules targeting bacterial peptidoglycan glycosyltransferase
Dr Alastair Parkes, Evotec, Oxfordshire, UK

12.35 Flash poster presentations

12.50 Lunch, exhibition and poster session

13.50 Discovery of new antibiotics
Prof Dave Spring, University of Cambridge, UK

14.35 Novel polymyxin derivatives for gram-negative infections: synthesis and SAR
Mrs Pamela Brown, Cantab Anti-Infectives, Hertfordshire, UK

15.05 Discovery of new antibiotics for drug resistant Neisseria gonorrhoeae
Dr Nawaz Khan, Discuva, Cambridge, UK

15.35 Refreshment break, exhibition and poster session

16.00 Novel topoisomerase inhibitors active against MDR gram-negative bacteria
Dr Cornelia Zumbrunn, Actelion Pharmaceuticals, Allschwil, Switzerland

16.30 Towards new antibiotics targeting penicillin-binding proteins
Prof Chris Schofield, University of Oxford, UK

17.15 Closing remarks

17.20 Wine reception

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